Picture of Yangdou Wei

Yangdou Wei B.Sc., M.Sc., Ph.D.


Faculty Member in Biology

CSRB 220.4

Research Area(s)

  • Cell Biology of Plant-Microbe Interactions
  • Plant Disease Resistance
  • Fungal Virulence and Pathogenicity
  • Pathogenomics


Seifbarghi, S., Borhan, M.H., Wei, Y., Ma, L., Coutu, C., Bekkaoui, D. and Hegedus, D.D. (2020). Receptor-like kinases BAK1 and SOBIR1 are required for necrotizing activity of a novel group of Sclerotinia sclerotiorum necrosis-inducing effectors. Front. Plant Sci. https://doi.org/10.3389/fpls.2020.01021

Liu, L., Qin, L., Zhou, Z.,  Hendriks, W.G.H.M., Liu, S., and Wei, Y. (2020). Refining the life cycle of Plasmodiophora brassicae. Phytopathology https://doi.org/10.1094/PHYTO-02-20-0029-R

Muirhead, K., Todd, C.D., Wei, Y., Bonham-Smith, P., and Pérez-López, E. (2020). ClubrootTracker: Helping to plan a clubroot-free farm. Plant Health Progress 21:185-187.

Sheng Wang, Qiang Li, Liang Zhao, Sanxiong Fu, Li Qin, Yangdou Wei, Yong-Bi Fu, and Hong Wang. (2020). Arabidopsis UBC22, an E2 able to catalyze lysine-11 specific ubiquitin linkage formation, has multiple functions in plant growth and immunity. Plant Science https://doi.org/10.1016/j.plantsci.2020.110520

Qin, L., Zhou, Z., Li, Q., Zhai, C., Liu, L., Quilichini, T.D., Gao, P., Kessler, S.A., Jaillais, Y., Datla, R., Peng, G., Xiang, D., and Wei, Y. (2020). Specific Recruitment of Phosphoinositide Species to the Plant-Pathogen Interfacial Membrane Underlies Arabidopsis Susceptibility to Fungal Infection. Plant Cell 32:1665-1688.

Pérez-López, E., Hossain, M.M., Tu, J., Waldner, M., Todd, C.D., Kusalik, A.J., Wei, Y. and Bonham-Smith, P.C. (2020).  Transcriptome analysis identifies Plasmodiophora Brassicae secondary infection effector candidates. J Eukaryot Microbiol. 67:337-351.

Xiang, D., Quilichini, T.D., Liu, Z., Gao, P., Pan, Y., Li, Q., Nilsen, K., Venglat, P., Esteban, E., Pasha, A., Wang, Y., Wen, R., Zhang, Z., Hao, Z., Wang, E., Wei, Y., Cuthbert, R., Kochian, L.V., Sharpe, A., Provart, N.J., Weijers, D., Gillmor, S., Pozniak, C.J. and Datla, R. (2019). The transcriptional landscape of polyploid wheat and their diploid ancestors during embryogenesis and grain development. Plant Cell 31:2888-2911.

Chang, A., Lamara, M., Wei, Y., Hao, H., Parkin, I.A.P., Gossen, B.D., Peng, G. and Yu, F.  (2019). A clubroot resistance gene in Brassica nigra resides in a genomic region homologous to chromosome A08 in B. rapa. BMC Plant Biology 19:224 https://doi.org/10.1186/s12870-019-1844-5

Irani, S., Todd, C., Wei, Y., Bonham-Smith, P. (2019). Changes in phenylpropanoid pathway gene expression in roots and leaves of susceptible and resistant Brassica napus lines in response to Plasmodiophora brassicae inoculation. Physiological and Molecular Plant Pathology 106:196-203.

Lahlali, R., Song, T., Chu, M., Karunakaran, C., Yu, F., Wei, Y., Peng, G. (2019). Synchrotron-based spectroscopy and imaging reveal changes in the cell-wall composition of barley leaves in defense responses to Blumeria graminis f. sp. tritici. Canadian Journal of Plant Pathology 41:457-467.

Ji, Y., Li, Q., Liu, G., Selvaraj, G., Zheng, Z., Zou, J. and Wei, Y. (2018). Roles of cytosolic glutamine synthetases in Arabidopsis development and stress responses. Plant and Cell Physiology 60:657-671.

Tu, J.Y., Bush, J., Bonham-Smith, P. and Wei, Y.D. (2018). Live cell imaging of Plasmodiophora brassicae - host plants interactions based on a two-step axenic culture system. MicrobiologyOpen 14:e765. doi: 10.1002/mbo3.765.

Wang, L., Wen, R., Wang, J., Xiang, D., Wang, Q., Zang, Y., Wang, Z., Huang, S., Li, X., Datla, R., Fobert, P.R., Wang, H., Wei, Y. and Xiao, W. (2018). Arabidopsis UBC13 differentially regulates two programmed cell death pathways in responses to pathogen and low-temperature stress. New Phytol. doi: 10.1111/nph.15435.

Pérez-López, E., Waldner, M., Hossain, M., Kusalik, A.J., Wei, Y., Bonham-Smith, P.C. and Todd, C.D. (2018). Identification of Plasmodiophora brassicae effectors - A challenging goal. Virulence 9(1):1344-1353.

Gu, Q., Yuan, Q., Zhao, D., Huang, J., Hsiang, T., Wei, Y. and Zheng, L. (2018). Acetyl-coenzyme A synthetase gene ChAcs1 is essential for lipid metabolism, carbon utilization and virulence of the hemibiotrophic fungus Colletotrichum higginsianum. Mol Plant Pathol. doi: 10.1111/mpp.12743.

Yan, Y., Yuan, Q., Tang, J., Huang, J., Hsiang, T., Wei, Y. and Zheng, L. (2018). Colletotrichum higginsianum as a model for understanding host-pathogen interactions: A Review. Int J Mol Sci. 19(7). pii: E2142. doi: 10.3390/ijms19072142.

Li, H., Li, X., Xuan, Y., Jiang, J., Wei, Y. and Piao, Z. (2018). Genome wide identification and expression profiling of SWEET genes family reveals its role during Plasmodiophora brassicae-induced formation of clubroot in Brassica rapa. Front Plant Sci. 9:207. doi: 10.3389/fpls.2018.00207.

Irani, S., Trost, B., Waldner, M., Nayidu, N., Tu, J., Kusalik, A.J., Todd, C.D., Wei, Y. and Bonham-Smith, P.C. (2018). Transcriptome analysis of response to Plasmodiophora brassicae infection in the Arabidopsis shoot and root. BMC Genomics 19(1):23. doi: 10.1186/s12864-017-4426-7.

Liu, L., Yan, Y., Huang, J., Hsiang, T., Wei, Y., Li, Y., Gao, J. and Zheng, L. (2017). A novel MFS transporter gene ChMfs1 is important for hyphal morphology, conidiation, and pathogenicity in Colletotrichum higginsianum. Front Microbiol. 8:1953. doi: 10.3389/fmicb.2017.01953.

Sudarshan, G.P., Kulkarni, M., Akhov, L., Ashe, P., Shaterian, H., Cloutier, S., Rowland, G., Wei, Y. and Selvaraj, G. (2017). QTL mapping and molecular characterization of the classical D locus controlling seed and flower color in Linum usitatissimum (flax). Sci Rep. 7(1):15751. doi: 10.1038/s41598-017-11565-7.

Zhou, T., Qin, L., Zhu, X., Shen, W., Zou, J., Wang, Z. and Wei, Y. (2017). The D-lactate dehydrogenase MoDLD1-mediated cellular metabolism is essential for growth and infection-related development in Magnaporthe oryzae. Environ Microbiol. 19(10):3938-3958.

Seifbarghi, S., Borhan, M.H., Wei, Y., Coutu, C., Robinson, S.J. and Hegedus, D.D. (2017). Changes in the Sclerotinia sclerotiorum transcriptome during infection of Brassica napus. BMC Genomics 18(1):266. doi: 10.1186/s12864-017-3642-5.

Li, Q., Shen. W., Zheng, Q., Tan, Y., Gao, J., Shen, J., Wei, Y., Kunst, L. and Zou, J. (2017). Effects of eIFiso4G1 mutation on seed oil biosynthesis. Plant J 90(5):966-978.

Bhadauria, V., Vijayan, P., Wei, Y. and Banniza, S. (2017). Transcriptome analysis reveals a complex interplay between resistance and effector genes during the compatible lentil-Colletotrichum lentis interaction. Sci Rep 7:42338. doi: 10.1038/srep42338.

Gu, Q., Chen, M., Huang. J., Wei, Y., Hsiang, T. and Zheng, L. (2017). Multifaceted roles of the Ras guanine-nucleotide exchange factor ChRgf in development, pathogenesis, and stress responses of Colletotrichum higginsianum. Phytopathology 107:433-443.

Li, Q., Zheng, Q., Shen, W., Cram, D., Fowler, D.B., Wei, Y. and Zou, J. (2015). Understanding the biochemical basis of temperature-induced lipid pathway adjustments in plants. Plant Cell 27:86-103.

Yang, L., Qin, L., Liu, G., Peremyslov, V.V., Dolja, V.V. and Wei, Y. (2014). Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens. Proc Natl Acad Sci U S A. 111(38):13996-14001.

Liu, L., Zhao, D., Zheng, L., Hsiang, T., Wei, Y., Fu, Y. and Huang, J. (2013). Identification of virulence genes in the crucifer anthracnose fungus Colletotrichum higginsianum by insertional mutagenesis. Microb Pathog. 64:6-17.

Bhadauria, V., Bett, K.E., Zhou, T., Vandenberg, A., Wei, Y. and Banniza, S. (2013). Identification of Lens culinaris defense genes responsive to the anthracnose pathogen Colletotrichum truncatum. BMC Genet. 14:31. doi: 10.1186/1471-2156-14-31.

Bhadauria, V., Banniza, S., Vandenberg, A., Selvaraj, G. and Wei, Y.D. (2013). Overexpression of a novel biotrophy-specific Colletotrichum truncatum effector CtNUDIX in hemibiotrophic fungal phytopathogens causes incompatibility with their host plants. Eukaryotic Cell 12:2-11.

Bhadauria, V., Banniza, S., Vandenberg, A., Selvaraj, G. and Wei Y. (2012). Alanine:glyoxylate aminotransferase 1 is required for mobilization and utilization of triglycerides during infection process of the rice blast pathogen, Magnaporthe oryzae. Plant Signal Behav. 7(9):1206-1208.

Bhadauria, V., Banniza, S., Vandenberg, A., Selvaraj, G. and Wei Y. (2012). Peroxisomal alanine: glyoxylate aminotransferase AGT1 is indispensable for appressorium function of the rice blast pathogen, Magnaporthe oryzae. PLoS One 7(4):e36266 (DOI: 10.1371/journal.pone.0036266).

Armstrong-Cho, C.L., Wang, J., Wei, Y.D. and Banniza, S. (2012). The infection process of two pathogenic races of Colletotrichum truncatum on lentil. Canadian Journal of Plant Pathology 34:58-67.

Menat J, Cabral AL, Perumal V, Wei Y.D. and Banniza S. (2012). Glomerella truncata: Another Glomerella species with an atypical mating system. Mycologia 104:641-649.

Bhadauria V, Banniza S, Vandenberg A, Selvaraj G, Wei Y. (2011). Cataloging proteins putatively secreted during the biotrophy-necrotrophy transition of the anthracnose pathogen Colletotrichum truncatum. Plant Signal Behav. 6:1462-1464.

Forseille, L., Geng, P., Wei, Y.D., Gossen, B.D. (2011). Molecular and morphological differentiation of Colletotrichum truncatum from scentless chamomile and selected crop species. Canadian Journal of Plant Pathology 33:512-524.

Bhadauria, V., Banniza, S., Vandenberg, A., Selvaraj, G. and Wei, Y.D. (2011). EST mining identifies proteins secreted at the hemibiotrophic switch of the anthracnose pathogen Colletotrichum truncatum. BMC Genomics 12:327 (DOI: 10.1186/1471-2164-12-327).

Feng, J., Bhadauria, V., Liu, G., Selvaraj, G., Hughes, G.R. and Wei, Y.D. (2011). Analysis of the promoter region of the gene LIP1 encoding triglyceride lipase from Fusarium graminearum. Microbiological Research 166:618-628.

Feng, J., Wang, F., Hughes, G.R., Kaminskyj, S. and Wei, Y.D. (2011). An important role for secreted esterase activity in disease establishment of the wheat powdery mildew fungus Blumeria graminis f. sp. tritici. Canadian Journal of Microbiology 57:211-216.

Nanjundappa, R.H., Wang, R., Xie, Y., Umeshappa, C.S., Chibbar, R., Wei, Y.D., Liu, Q. and Xiang, J. (2011). GP120-specific exosome-targeted T cell-based vaccine capable of stimulating DC- and CD4(+) T-independent CTL responses. Vaccine 29:3538-3547.

Liu, G., Ji, Y., Bhuiyan, N.H., Pilot, G., Selvaraj, G., Zou, J. and Wei, Y.D.  (2010). Amino acid homeostasis modulates salicylic acid-associated redox status and defense responses in Arabidopsis. Plant Cell 22:3845-3863.

Shen, W., Li, J., Dauk, M., Huang, Y., Periappuram, C., Wei, Y.D. and Zou, J. (2010). Metabolic and transcriptional responses of glycerolipid pathways to perturbation of glycerol-3-phosphate in Arabidopsis. J Biol Chem 285:22957-22965.

Feng, J., Wang, F., Liu, G.S., Greenshields, D., Shen, W., Kaminskyj, K., Hughes, G.R., Peng, Y.L., Selvaraj, G., Zou, J. and Wei, Y.D. (2009). Analysis of a Blumeria graminis secreted lipase reveals the importance of host epicuticular wax components in fungal development. Mol Plant Microbe Interact 22:1601-1610.

Bhuiyan N.H, Selvaraj G, Wei Y.D., King J. (2009). Gene expression profiling and silencing reveal that monolignol biosynthesis plays a critical role in penetration defence in wheat against powdery mildew invasion. J Exp Bot 60:509-521.

Ding, S., Mehrabi, R., Koten, C., Kang, Z., Wei, Y., Seong, K., Kistler, H.C. and Xu, J.R. (2009). Transducin beta-like gene FTL1 is essential for pathogenesis in Fusarium graminearum. Eukaryot Cell 8:867-876.

Umeshappa, C.S., Huang, H., Xie, Y., Wei, Y.D., Mulligan, S.J., Deng, Y. and Xiang J. (2009). CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses. J Immunol 182:193-206.

Liu, G., Greenshields, D.L., Sammynaiken, R., Hirji, R.N., Selvaraj, G. and Wei, Y.D. (2007). Targeted alterations in iron homeostasis underlie plant defense responses. J Cell Sci 120:596-605.

Bhuiyan, N.H., Liu, W., Liu, G., Selvaraj, G., Wei, Y.D. and King, J. (2007). Transcriptional regulation of genes involved in the pathways of biosynthesis and supply of methyl units in response to powdery mildew attack and abiotic stresses in wheat. Plant Mol Biol 64:305-318.

Liu, G., Kennedy, R., Greenshields, D.L., Peng, G., Forseille, L., Selvaraj, G. and Wei, Y.D.  (2007). Detached and attached Arabidopsis leaf assays reveal distinctive defense responses against hemibiotrophic Colletotrichum species. Mol Plant Microbe Interact 20:1308-1319.

Greenshields, D.L., Liu, G., Feng, J., Selvaraj, G. and Wei, Y.D. (2007). The siderophore biosynthetic gene SID1, but not the ferroxidase gene FET3, is required for full Fusarium graminearum virulence. Mol Plant Pathol 8:411-421.

Hao, S., Liu, Y., Yuan, J., Zhang, X., He, T., Wu, X., Wei, Y.D., Sun, D. and Xiang, J. (2007). Novel exosome-targeted CD4+ T cell vaccine counteracting CD4+25+ regulatory T cell-mediated immune suppression and stimulating efficient central memory CD8CTL responses. J Immunol 179:2731-2740.

Shen, W., Wei, Y.D., Dauk, M., Tan, Y., Taylor, D.C., Selvaraj, G. and Zou, J. (2006). Involvement of a glycerol-3-phosphate dehydrogenase in modulating NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell 18:422-441.

Feng, J., Liu, G., Selvaraj, G., Hughes, G.R. and Wei, Y.D. (2005). A secreted lipase encoded by LIP1 is necessary for efficient use of saturated triglyceride lipids in Fusarium graminearum. Microbiology 151:3911-3921.

Greenshields, D., Liu, G., Selvaraj, G. and Wei, Y.D. (2005). Differential regulation of quinone reductase genes in powdery mildew infected wheat. Planta 222:867-875.

Liu, G., Sheng, X., Greenshields, D.L., Ogieglo, A., Kaminskyj, S., Selvaraj, G. and Wei, Y.D. (2005). Profiling of wheat class-III peroxidase genes derived from powdery mildew attached epidermis reveals distinct sequence-dependent expression patterns. Mol Plant Microbe Interact 18:730-741.

Wei, Y.D., Shen, W., Dauk, M., Wang, F., Selvaraj, G. and Zou, J. (2004). Targeted-gene disruption of glycerol-3-phosphate dehydrogenase in Colletotrichum gloeosporioides reveals evidence that glycerol is a transferred nutrient from host plant to fungal pathogen. J Biol Chem 279:429-435.

Wei, Y.D., Shih, J., Li, J. and Goodwin, P.H. (2002). Two pectin lyase genes, pnl-1 and pnl-2, from Colletotrichum gloeosporioides f. sp. malvae differ in a cellulose-binding domain and in their expression during infection of Malva pusilla. Microbiology 148:2149-2157.

Zou, J., Wei, Y.D., Jako, C., Kumar, A., Selvaraj, G. and Taylor, D.C. (1999). The Arabidopsis thaliana TAG1 mutant has a mutation in a gene encoding a homolog of the mammalian diacylglycerol acyltransferase. Plant J 19:645-654.

Wei, Y.D., Zhang, Z., Andersen, C.H., Schmelzer, E., Gregersen, P.L., Collinge, D.B., Smedegaard‑Petersen, V. and Thordal‑Christensen, H. (1998). An epidermis/papilla‑specific oxalate oxidase‑like protein in the defence response of barley attacked by the powdery mildew fungus. Plant Mol Biol 36:101‑112.

Thordal‑Christensen, H., Zhang, Z., Wei, Y.D. and Collinge, D.B. (1997). Subcellular localization of H2O2 in plants, H2O2 accumulation in papillae and hypersensitive response during the barley‑powdery mildew interaction. Plant J 11:1187‑1194.

Wei, Y.D, Collinge, D.B, Smedegaard-Petersen, V. and  Thordal-Christensen, H. (1996). Characterization of the transcript of a new class of retroposon-type repetitive element cloned from the powdery mildew fungus, Erysiphe graminis. Mol Gen Genet. 250(4):477-482.

Wei, Y.D., de Neergaard, E., Thordal Christensen, H., Collinge, D.B. and Smedegaard Petersen, V. (1994). Accumulation of a putative guanidine compound in relation to other early defence reactions in epidermal cells of barley and wheat exhibiting resistance to Erysiphe graminis f. sp. hordei. Physiological and Molecular Plant Pathology 45:469-484.

Wei, Y.D. and Mortensen, C.N. (1992). Bioassay of toxins as a diagnostic method for Pseudomonas syringae pathovars. Journal of Phytopathology 134:110-116.

Teaching & Supervision

Biol 120  The Nature of Life

Biol 222  The Living Plant

Biol 325  Plant Cells and Tissues

Biol 345  Introductory Plant Pathology

Biol 841  Advanced Plant Pathology